Drug NCTF 135 – mesotherapy for any age


Composition and properties

The mesotherapy cocktail NCTF 135 HA+, like its predecessors (NCTF 135 and NCTF 135 HA), consists of hyaluronic acid of non-animal origin. The most concentrated drug in the line - the content of the main component in it is 10 mg / ml. The cocktail contains 12 vitamins, 2 antioxidants, 5 nucleosides, 6 minerals, 6 coenzymes and 20 amino acids (+ 3 related compounds).

Hyaluronic acid is of primary importance for the longest possible preservation of skin youth due to its hydrating properties. Dehydration of the dermis and epidermis is a factor that has an extremely negative effect on its visual condition. Dehydration is caused by both natural age-related changes and other etiological reasons - abuse of insolation, living in environmentally unfavorable conditions, smoking, systemic diseases, etc.

Injections of preparations based on hyaluronic acid are a sure and affordable way to maintain the beauty of the skin.

In addition to hyaluronic acid, NCTF 135 HA+ includes:

  • Vitamins (A, C, E, I ) – protect cell membranes from harmful exogenous influences, tone capillary walls, lighten melasma and chloasma, neutralize inflammation, participate in biochemical and metabolic reactions;
  • B vitamins – inhibit the aging process, accelerate local metabolism, increase cellular respiration, regulate carbohydrate, protein and lipid metabolism in cells, stimulate the production of fibroblasts;
  • Minerals – adjust the ionic balance in cells, optimize tissue metabolism, activate lymph flow and blood microcirculation;
  • Amino acids - have a positive effect on the fibers of the elastin-collagen framework, restore elasticity and firmness to the skin, increase protective forces;
  • Nucleotides - produce DNA and RNA acids, strengthen their molecular chains, organize amino acid compounds in the process of protein synthesis;
  • Antioxidants – prevent free radical oxidation in the cells of the epidermis and dermis;
  • Coenzymes - provide detoxification and eliminate decay products from tissues, help accelerate the processes of proliferation and regeneration in tissues, and establish energy balance in cells.

Composition of NCTF 135 line drugs

The company's products preserve as much as possible the active ingredients with a high degree of purification of the solutions. This is possible thanks to sterilization using double ultrafiltration. The preparations differ in the content of hyaluronic acid per 1 ml:

  • NCTF 135 + “Innovative” - 0.025 mg;
  • filorga nctf 135 HA “Enriched” - 5 mg;
  • NTCF 135 HA + “Extra Fortified” - 10 mg.

Hyaluronic acid retains a large number of water molecules, which contributes to deep hydration of the skin and normalization of the water-mineral balance of tissues. It has an anti-inflammatory effect; stimulates cellular regeneration, cell growth, production of collagen and elastin proteins by fibroblasts; increases the antioxidant (reducing the formation of free radicals) properties of cocktail components.

The remaining components are the same in all three products in the line.

Main active elements of the formula:

  1. Vitamins A, C, E, inositol, which have antioxidant, anti-inflammatory, antitumor properties. They also reduce the permeability of the vascular wall, reduce hyperpigmentation and stimulate cellular regeneration, oxidize amino acids from which collagen and elastin are formed.
  2. Vitamins B 1-12 are involved in all types of metabolism and oxidation and reduction processes, activate cell division, increase the speed of impulses from nerve endings to tissue cells, and promote the breakdown of fats.
  3. Amino acid complex. Proline and hydroxyproline are of primary importance for the skin - these are the main proteins of collagen, which give it high strength. The amino acids threonine and serine are part of elastin fibers and are involved in the construction of cell membranes.
  4. Minerals necessary for the implementation of intra- and extracellular biochemical reactions in metabolic tissue processes, regulation of cell acidity and the intercellular environment.
  5. Nucleotides that form intracellular information transmission structures (DNA and RNA).
  6. Coenzymes are catalysts for the speed of biochemical reactions, and therefore metabolic processes. They increase the rate of tissue repair.
  7. The antioxidant glutathione, which is sometimes called the elixir of youth and health. Together with others (vitamins), it slows down oxidative processes, thereby slowing down the aging process of tissues.

Scope of application of NCTF 135 HA+ in cosmetology

The drug NCTF 135 HA+ is used in cosmetology for mesotherapy and biorevitalization procedures. They are injectable and non-injectable. In the second case, the cocktail penetrates the skin using a mesoscooter, mesoinjector or devices (special infrared laser, etc.). The injection version of the cocktail gives a more noticeable and prolonged effect, which is why cosmetologists prefer it. NCTF 135 HA+ infusion techniques – papular, superficial/median nappage or linear retrograde.

The drug is administered to the following areas:

  • Face;
  • Neck and décolleté area.

For mesotherapy of the scalp, NCTF 135 and NCTF 135 HA are most often used. Purposes of drug administration:

  • Awakening the internal potentials of the skin;
  • Enriching the skin with vitamins, minerals and other valuable nutrients;
  • Deep hydration and nutrition of the skin;
  • Optimization of cellular respiration, lymphatic drainage, local blood circulation;
  • Acceleration of regenerative and proliferative processes in cells and tissues (especially important during rehabilitation after aggressive procedures and operations);
  • Increased skin tone and turgor;
  • Relief of pathological activity of the sebaceous and sweat glands;
  • Cleansing and detoxification.

Types of the drug and their characteristics

The basis of the drug is unstabilized hyaluronic acid (analogous to natural one). In addition to it, the NCTF includes:

  • 12 vitamins - A, E, C, group B - they make the skin elastic and strong, stimulate metabolism and collagen synthesis, strengthen the walls of skin capillaries, have an anti-inflammatory and restorative effect;
  • 23 amino acids, including asparagine, threonine, lysine, proline - they are necessary to maintain active production of collagen and elastin;
  • 4 mineral elements - they stimulate metabolic reactions, normalize water balance in the epidermal layers and dermis;
  • 5 nucleic acids – the correct combination of amino acids during protein synthesis depends on them;
  • 6 coenzymes - they make metabolic reactions and skin cell restoration processes more active;
  • ascorbic acid and glutathione are antioxidants that neutralize free radicals.

The Filorga NCTF 135 series includes three preparations that differ in the concentration of hyaluronic acid:

  1. Innovative NCTF . The product is recommended for women under 30 years of age. Helps slow down age-related skin aging and eliminate signs of photoaging. Intensively moisturizes skin tissue. Gives a noticeable positive effect in the treatment of acne, acne, seborrhea, and atrophic scars. Suitable for hair therapy, helps stop alopecia areata.
  2. Enriched with NCTF . Recommended for women 30-35 years old. Eliminates the first symptoms of age-related skin changes, as well as signs of fatigue and the influence of stress factors. Intensively moisturizes epidermal tissue. Helps get rid of unexpressed skin defects: shallow folds, atrophic formations. Used in the treatment of rosacea, strengthens capillary walls.
  3. Extra enriched NCTF. Intended for mature women: 35 years and older. Effectively eliminates age-related changes: shallow and medium folds, relief defects, sagging. Intensely moisturizes and restores healthy appearance to dehydrated skin. Prevents photoaging and dermatological problems associated with stress and menopausal hormonal changes. It is used for the treatment of rosacea, photodermatitis, to prepare the skin for deep chemical peeling, laser cleaning , and plastic surgery.

The series is complemented by Filorga NCTF Reverse restoring anti-aging cream with vitamins, collagen and hyaluronic acid.

Indications for injections NCTF 135 HA+

Procedures using NCTF 135 HA+ are indicated for the following defects:

  • Thinning, weakening, dehydration of the skin;
  • Looseness, sagging, pasty skin;
  • Gravitational ptosis of soft tissues of the face I-II degree;
  • Sharp and obvious wrinkles, grooves, folds;
  • “Stressed” skin (dullness and laxity of the skin in people living in metropolitan areas, working in air-conditioned rooms, experiencing chronic stress, and having a nicotine addiction);
  • Degenerative skin changes in the pre- and postmenopausal period;
  • Excessive oily skin;
  • Open and closed comedones;
  • Acne;
  • Atrophic scars.

Like its predecessors, the mesotherapy cocktail NCTF 135 HA+ is available in sterile 3 ml bottles. One procedure requires from ½ to 1 bottle of the drug. The intensive course consists of 4-6 sessions with an interval of 2-3 weeks.

NCTF 135 range

The NCTF 135 line consists mainly of three cocktails, which differ significantly in the concentration of additional hyaluronic acid:


Innovative (+) – 0.025 milligrams of hyaluronic acid per 3 milliliters;

Enriched (HA) – 5 milligrams of hyaluronic acid per 3 milliliters;

Extra-enriched (HA+) – 10 milligrams of hyaluronic acid per 3 milliliters.

Innovative +

This cocktail is intended for clients under the age of thirty and is used for:

  1. Deep skin hydration;
  2. Carrying out mesotherapy for hair, diffuse thinning, focal baldness;
  3. Treatment of atrophic scars;
  4. Correction of problematic skin, seborrhea, acne and so on;
  5. Prevention and correction of early signs of photo- and age-related aging.


The classic course consists of four to six sessions, which are held at intervals of seven to fourteen days. After which you need to undergo about three more maintenance sessions with breaks of ninety days. The technique for administering this drug is papular, that is, injections are used in the volume required to create a papule or ball, to increase the accumulation of components in the layers of the skin, or superficial and medium nappage, that is, a series of micro-injections of 0.02 milliliters at the dermal and epidermal levels.

Enriched with HA

This cocktail is intended for patients aged thirty to thirty-five years and is used for:

  1. Deep skin hydration;
  2. Treatment of rosacea;
  3. Strengthening vascular walls;
  4. Treatment of stressed skin due to the formation of chronic fatigue syndrome and severe psychological stress, and so on;
  5. Correction of small age-related defects of the skin - sagging, atrophy, fine wrinkles;
  6. Prevention and correction of early signs of photo- and age-related aging.


The duration of the course is approximately the same as above, a series of four to six treatments every one to four weeks and three maintenance sessions every ninety days. The insertion technique is also papular, median and superficial nappage, linear-retrograde needle, which is inserted to the required depth at a specific angle. The administration of this drug is carried out by reversing the needle; in other words, it fills the linear channel formed by the needle in the dermis.

Extra enriched HA+

This cocktail is intended for patients aged thirty-five and above and is used for:

  1. Enhanced hydration of dehydrated skin;
  2. Treatment of stressed skin;
  3. Prevention of degenerative changes in the skin during the period of hormonal changes;
  4. As an additional remedy in the complex therapy of patients with photodermatoses;
  5. Preparation and recovery of patients during deep chemical peels, laser and mechanical resurfacing, as well as plastic surgery;
  6. Treatment of rosacea;
  7. Prevention during intense insolation (after or before traveling to hot regions, during mountaineering, windsurfing, skiing, visiting a solarium), as well as to prevent sunburn, in patients with skin sensitive to ultraviolet radiation;
  8. Correction of age-related defects of the skin - medium and low severity of wrinkles, uneven microrelief, sagging.

The course of treatment generally consists of three to five treatments at intervals of two to three weeks, and two maintenance sessions every ninety days. The technique is papular, medium nappage and linear-retrograde.

Contraindications drug price

Drugs in the NCTF 135 line are not used for:

  • Exacerbation of chronic or in the presence of current acute inflammatory diseases;
  • Oncological pathologies;
  • Personal intolerance to certain substances of the drug;
  • Various types of blood clotting disorders;
  • The period of treatment with anticoagulants;
  • Lactation;
  • Pregnancy.


NCTF 135 is considered the first mesomedicine in the world to receive the European Safety Mark for medical devices. Absolutely the entire NCTF 135 line has passed the necessary quality tests in the Russian Federation, and has received approval from the ministries of health of other countries.

The average price of these cocktails for one session in clinics in the capital is as follows:

  1. NCTF 135 – from 3600 to 5000 rubles per procedure;
  2. NCTF 135 NA – from 5000 to 7000 per procedure;
  3. NCTF 135 HA+ - from 7000 to 8000 per procedure.

Effect of NCTF 135 HA+

A full course of mesotherapy with NCTF 135 HA+ gives the following results:

  • Smoothing out small creases and wrinkles;
  • Reduction of structural grooves and folds;
  • Renewal and refreshment of the skin;
  • Healthy complexion and light blush;
  • Internal “highlighting” of the skin;
  • Evens out skin tone and texture;
  • Lightening of hyperpigmentation;
  • Elimination of dark circles and puffiness under the eyes;
  • Cleansing pores and removing comedones;
  • Elimination of acne;
  • Camouflage spots and acne scars.

Indications for use

Biorevitalization NCTF 135 is recommended for rejuvenation and general improvement of the condition of skin tissue. The drug is used for:

  • prevention of early skin aging;
  • eliminating existing age-related defects;
  • auxiliary therapy of seborrhea, rosacea, inflammatory formations;
  • preparing the skin for intensive cosmetic procedures, as well as for rehabilitation after these operations;
  • improving the external condition of the skin, eliminating a painful and tired appearance;
  • fight wrinkles, improve relief;
  • therapy of scars, stretch marks, burns, excess pigmentation.
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