NOW DMAE, DMAE, Dimethylaminoethanol 250 mg - 100 capsules

Dimethylaminoethanol (DMAE): additive

Due to the fact that studies on the toxicity of dimethylaminoethanol were carried out relatively recently, drugs containing it were initially produced in the form of a food additive. They typically contain natural DMAE from salmonids and are marketed as cognitive enhancers and vitality boosters. In this form, it is much easier to obtain the required amount of dimethylaminoethanol , since the natural production of this compound by the brain occurs only in small quantities, and regular consumption of products with it, such as sprat, sardines, anchovies and salmon, is not always possible.

Indications for use

NOW DMAE 250 mg 100 capsules supplement should be included in the diet for the prevention of:

• diseases of the heart and its system;
• disorders in brain function;
• depression;
• cerebrovascular accidents.

The DMAE complex is included in the diet to improve intellectual activity and increase the body’s energy. It should be remembered that the dietary supplement is not a medicine. The drug "DMAE" is prescribed only for preventive purposes.

Dimethylaminoethanol (DMAE): properties

The action of dimethylaminoethanol is very multifaceted. The main properties of this compound include the following:

• DMAE is a powerful antioxidant and protects cells from the destructive effects of free radicals;
• stimulates brain activity, improves memory and concentration;
• has an immunostrengthening and anti-inflammatory effect;
• improves blood chemistry;
• ensures complete saturation of cells and tissues with oxygen;
• promotes water retention in connective tissues;
• gives a surge of vigor and energy;
• rejuvenates the body at the cellular level;
• helps increase the conductivity of nerve impulses from the brain to the muscles, significantly tightening them;
• cleanses the body of dead cells and their waste;
• improves mood, normalizes sleep;
• increases skin elasticity.

Effects:

1. Life extension. Most people know this effect; the experiment was carried out in 1973 on mice, and they lived 30-50% longer than their counterparts.

   

2. DMAE improves and synchronizes, to a large extent, the transmission of signals between the hemispheres of the brain according to the results of the EEG (study of 1986). This indicates better integrity of the brain, not only memory and learning, but also other brain functions. You won't become super smart, but your brain will be like a fresh computer or a website with well-written code. (1986;18:2069-2086)

   

3. Learning ability improves. An experiment on children, banal, some were given a pacifier, others DMAE, no one knew who had what, after 3 months the group with DMAE showed the best progress in academic performance, the numbers are not crazy, but not an accident either. (1975;17:534-540)

   

4. Fatigue, depression decreases. There were 2 similar studies, one had 52 people, the other 100, both groups improved their health. (1959:195-244)
5. Antioxidant effect. Free radical scavenging. However, it is insignificant. (1974;72:265)
6. Presumably, dopamine levels increase. Dimethylglycine and Trimethylglycine are created. This together gives the effect of light stimulation and concentration.

Dimethylaminoethanol (DMAE): Applications

Dimethylaminoethanol has found wide application in human life. It is used in the chemical, textile and paint industries, as well as for water purification, but its main areas of application are pharmaceuticals and cosmetology.

based on DMAE , which have proven themselves in:

• diseases of blood vessels and heart;
• cerebrovascular accidents;
• increased physical and emotional stress;
• memory loss and Alzheimer's disease;
• attention deficit hyperactivity disorder (ADHD).

DMAE , along with creatine, whey protein and other sports supplements, is used by bodybuilders to stimulate muscle growth.

In addition, it is advisable to use drugs with dimethylaminoethanol as a preventive measure for age-related changes in the body, especially in combination with a complex of vitamins.

Cosmetics manufacturers often use DMAE as a base for the production of care products for aging skin, as well as in the production of soaps and shampoos.

More DMAE in cosmetics

Another collection of creams and serums based on DMAE – Source Naturals, Skin Eternal Cream. A line based on DMAE, alpha-lipoic acid and vitamin C. This is one of the most studied safe anti-aging combinations loved by cosmetologists:

Source Naturals, Skin Eternal Cream, 56.7 g

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RUB 1,283

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Source Naturals, Skin Eternal Cream, 4 oz (113.4 g)

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RUB 2,245

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Source Naturals, Skin Eternal Serum, 1.7 fl oz (50 ml)

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RUB 1,604

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Source Naturals, Skin Eternal DMAE Serum, 1.7 fl oz (50 ml)

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RUB 1,604

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Source Naturals, Skin Eternal Hyaluronic Serum, 1.7 fl oz (50 ml)

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RUB 1,604

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Source Naturals, Skin Eternal Day Cream, 113.4 g

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RUB 2,406

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Source Naturals, Skin Eternal Cream with DMAE, 56.7 g

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RUB 1,336

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Source Naturals, Skin Eternal Hyaluronic Serum, 1 fl oz (30 ml)

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976 rub.

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Dimethylaminoethanol (DMAE): in cosmetology

Dimethylaminoethanol is a very popular and sought-after drug in modern cosmetology. This is due to its ability of DMAE to increase the amount of acetylcholine in tissues. Acetylcholine is a substance necessary to maintain muscle tone and normal functioning, but over the years its amount in the body steadily decreases, which is manifested not only by a decrease in muscle tone and loss of elasticity of the skin, but also by increased fatigue, deterioration of memory and thinking, and depression. The only way to slow down these processes is to replenish the lack of active acetylcholine through internal and external use of DMAE .

The effectiveness and safety of the use of dimethylaminoethanol in cosmetology has been proven relatively recently, but the results of the studies have caused an unprecedented surge of interest in this compound and, as a result, the emergence of new cosmetic anti-aging products for superficial (cream, serum) and intradermal (mesotherapy) use.

Dimethylaminoethanol (DMAE): for skin

Based on the above, the benefits of dimethylaminoethanol for the skin become obvious. Under the influence of this compound, aging skin of the face, neck and décolleté regains smoothness and elasticity. However, this happens not only due to an increase in the amount of acetylcholine, although this is a determining factor. The complex anti-aging effect is achieved thanks to the ability of DMAE to act in several directions at once, namely:

• strengthen cell membranes;
• increase the level of metabolic processes in the skin;
• remove waste and toxins, in particular lipofuscin, which accumulates in cells over the years and causes age spots;
• neutralize free radicals that negatively affect the synthesis of elastin and collagen.

Description of properties

NOW Foods DMAE dietary supplement is based on dimethylaminoethanol. This is an amino alcohol, which in the body is converted into acetylcholine (a compound whose main task is to transmit and regulate signals from one nerve cell to another). Amino alcohol is found in small amounts in the brain.

Dimethylaminoethanol acts as an effective neurotransmitter that ensures normal functioning of the central nervous system and brain. A lack of acetylcholine is manifested by lethargy, irritability, slow reactions, and impaired cognitive functions.

When taken regularly, the dietary supplement "DMAE" can improve the functioning of the entire body.

The effects of use are as follows:

• brain activity is stimulated and, accordingly, human performance, concentration and memory improve;
• the sleep-wake pattern is normalized;
• cognitive abilities improve;
• the process of tissue oxygenation is enhanced;
• the toxic enzyme lipofuscin is destroyed in the body, which is a brown molecular waste that poisons cells and leads to their premature death, promotes the development of necrosis;
• the elasticity of the skin increases;
• the process of withering of the dermis slows down;
• energy exchange is enhanced, and therefore the dietary supplement is in high demand among athletes;
• the lipid barrier of the skin is restored;
• blood microcirculation increases;
• the overall well-being of a person improves.

In addition, the DMAE complex has a pronounced antioxidant property. The substances contained in its base are able to neutralize free radicals that destroy cells and provoke premature aging of the body.

Regular intake of the dietary supplement “DMAE” in capsules can improve health, mood and, accordingly, quality of life.

Dimethylaminoethanol (DMAE): lifting

The lifting effect of topical use of dimethylaminoethanol was officially confirmed after a double-blind study in 2002. It was found that regular application of 3% DMAE to the skin of the face significantly increases its elasticity, reduces the severity of wrinkles on the forehead and in the eye area, and these changes are long-term. In 2005, the safety of long-term (up to 1 year) use of dimethylaminoethanol . Moreover, DMAE to have a cumulative effect, i.e. the result depends on the duration of use of the product.

Dimethylaminoethanol (DMAE): mesotherapy

Recently, one of the most popular anti-aging salon procedures is mesotherapy with dimethylaminoethanol . Its relevance is due to the fact that:

• a positive result is noticeable immediately after the first session;
• the effect lasts for a long time (maintenance procedures need to be carried out only once every six months);
• mesotherapy with DMAE can act as an alternative to surgical correction of facial contours;
• this procedure is safe, since dimethylaminoethanol is of organic origin and is well tolerated by the body;

The essence of mesotherapy with DMAE is the sequential administration of the drug using the micropapule method. The course of such treatment, as a rule, ranges from 3 to 6 procedures, on average 10 minutes each. The list of indications for the use of injections with DMAE is quite extensive - in addition to problems associated with a natural decrease in the tone of the muscles of the face and body, this therapy is effective for:

• cellulite;
• age spots;
• stretch marks on the skin after childbirth or weight loss;
• scars from burns, injuries and surgical interventions;
• rosacea;
• skin inflammations;
• defects after unsuccessful cases of using botulinum toxin (Botox);
• baldness.

Dimethylaminoethanol (DMAE): drugs

Preparations with dimethylaminoethanol have recently become increasingly popular and their range is constantly expanding. Let's look at some of them below.

Dimethylaminoethanol (DMAE): Now Foods

1). Dimethylaminoethanol capsules from the famous American company Now Foods . The action of this dietary supplement is aimed mainly at improving brain activity and increasing the production of neurotransmitters, without which the transmission of nerve signals to the brain is impossible. The drug meets international quality standards, so there is no doubt about its effectiveness and safety. It works equally well either alone or in combination with other dietary supplements, such as Ginkgo Biloba, tyrosine and other means for restoring the nervous system.

Recommendations for use: take 1 capsule 1-3 times a day, preferably between meals.

Dimethylaminoethanol (DMAE): Twinlab

2). No less popular is the drug dimethylaminoethanol (DMAE) “DMAE Caps” from the manufacturer Twinlab . Each capsule contains 100 mg of high quality DMAE (2-dimethylaminoethanol), manufactured in our own modern center in accordance with the highest quality control requirements. In the production of this dietary supplement, only natural ingredients are used, so it is suitable for people suffering from allergies or on a special diet. Unlike most dietary supplements, the packaging of this drug is made of glass, which guarantees long-term preservation of the freshness and quality of the product.

Directions for use: Take 1 capsule daily or as directed by a physician.

Dimethylaminoethanol (DMAE): Reviva Labs

3). Among the variety of products containing dimethylaminoethanol , cosmetics for skin care occupy a special place. For example, Firming Eye Serum with DMAE “Firming Eye Serum” from Reviva Labs . Its advanced formula contains a whole range of useful substances. The main components of the serum, in addition to dimethylaminoethanol , are peptides that help get rid of dark circles under the eyes, as well as antioxidants - alpha-lipoic acid and vitamin C, designed to protect delicate skin from harmful environmental factors. In addition, the product contains hyaluronic acid, lecithin, sunflower and olive oils.

Recommendations for use: Apply a small amount of serum with gentle patting movements to the upper eyelid and area under the eyes in the morning or evening.

Questions about the product DMAE 250 Maxler (100 capsules)

Dimethylaminoethanol (DMAE): analogues

Dimethylaminoethanol is a unique compound that has virtually no analogues. However, some of its properties are also inherent in other nutritional supplements.

4). For example, Omega-3 medications also help maintain the health of the cardiovascular and nervous systems. In particular, Omega-3 capsules “Omega-3, Lemon” with lemon flavor from Nordic Naturals promote normal heart function, support brain activity and ensure good health. Moreover, unlike ordinary fish oil, these capsules do not have a characteristic odor, although they are made exclusively from natural raw materials obtained in wild natural conditions.

Recommendations for use: take 2 capsules per day on an empty stomach or with food.

5). DMAE , other active compounds can also have an anti-aging effect on the skin The latter is a powerful antioxidant, and is deservedly called the “elixir of youth”, since, penetrating into the deep layers of the skin, it helps to increase the production of elastin, collagen fibers and hyaluronic acid, which has a beneficial effect on the condition of the epidermal layer. Thanks to its abilities, coenzyme Q10 is one of the most popular components of anti-aging cosmetics. A huge number of anti-wrinkle creams are made based on it, and one of them is “Wrinkle Therapy, with CoQ10 & Rosehip, Day Creme” from Avalon Organics . This product helps to activate cellular renewal, which in turn increases the firmness and elasticity of the skin and prevents the formation of new wrinkles. In addition to the coenzyme itself, the cream contains many other organic ingredients, such as Shea butter, cocoa butter, arnica extract, chamomile extract, etc. All these ingredients help reduce the visual signs of aging of the skin, making it soft and healthy.

6). As for the ability of DMAE to influence muscle mass, among sports supplements there are many drugs with a similar effect. For example, one of the most favorite supplements of bodybuilders is BCAA, because it includes 3 essential amino acids at once, which have a direct effect on the growth of new muscle tissue, accelerate muscle recovery after physical activity, and improve metabolism. Among the many drugs, it is worth highlighting “BCAA 5000 Powder, Instantized” from Optimum Nutrition . This sports supplement is an instantized powder made using patented technology, thanks to which it is perfectly dissolved and absorbed, allowing you to get maximum benefits.

Directions: 1 powder diluted in 8-10 ounces of water or beverage and taken without food 30-45 minutes before or immediately after exercise.

Dimethylaminoethanol (DMAE): capsules

Among oral drugs with dimethylaminoethanol capsules are the most convenient. They are easy to dose and swallow, and the protective shell allows the active substances to be delivered to the small intestine without loss, where they are absorbed. Typically each capsule contains between 100 mg and 500 DMAE . As additional components, they may also include plant extracts and vitamins (most often, vitamin E, vitamin B6, vitamin B12, vitamin C and folic acid).

Dimethylaminoethanol (DMAE): in creams

For external application as daily care and skin rejuvenation, dimethylaminoethanol is used in creams. At the moment, products are produced in various price categories.

1). Among the available creams with DMAE , one should highlight the product “Alpha Lipoic Acid, Vitamin C Ester & DMAE Cream” from Reviva Labs . This night cream effectively fights all signs of skin aging, thanks to a unique formula that combines 3 active ingredients:

• DMAE,
• alpha lipoic acid,
• Vitamin C ester.

As auxiliary components, the product includes advanced palmitoyl Tripeptide-5, as well as Aloe Vera extract, phospholipids, stearic acid, vitamin E and jojoba oil.

Recommendations for use: massage the cream onto the skin of the face and neck at night.

2). Among cosmetic products with DMAE in a higher price category, Protective and Regenerating Cream “Enviroderm Creme” from Russell Organics . Its rich composition perfectly rejuvenates the skin, moisturizes it and protects it from adverse environmental conditions. This cream is suitable for any skin type, but it is especially effective if you have sensitive or dehydrated skin.

In addition to DMAE , the active ingredients include a large number of plant extracts and oils, vitamin A, vitamin C, vitamin B5, vitamin E, methylsulfonylmethane, etc.

Recommendations for use: Apply morning and evening to well-cleansed facial skin.

Dimethylaminoethanol or DMAE in mesotherapy

Operating principle and functions of DMAE

Once in the body, dimethylaminoethanol is transformed into acetylcholine, a substance that mediates between nerve cells and muscle tissue. In its natural state, this neurotransmitter is produced by the body, but as the nervous system ages, the level of its production decreases. As a result, muscle tone decreases. DMAE allows you to reverse the aging process: thanks to external and internal use of the drug, it is possible to increase the level of acetylcholine, thereby improving muscle response and skin condition.

Dimethylaminoethanol also has a cleansing effect, removing lipofuscin from the body. This “aging pigment” accumulates in the human body throughout life. In older people, the proportion of lipofuscin in the body's cells can reach 30%. How dangerous is this substance? It clogs mitochondria and poisons the intracellular space, resulting in the body being constantly intoxicated.

Another advantage of DMAE is that it has a positive effect on blood composition and improves oxygen metabolism. In addition, the drug acts as an antidepressant. Dimethylaminoethanol increases energy status, due to which mood significantly improves, a surge of strength is felt, and sleep becomes stronger and better quality. Feeling good has a positive effect on your appearance.

How DMAE works on the skin

Long-term studies show that dimethylaminoethanol has antioxidant, anti-inflammatory, and immunomodulatory properties . In cosmetology, it is used as an anti-aging agent for mesotherapy, aimed at improving complexion, smoothing out fine wrinkles, increasing elasticity and skin turgor.

Since DMAE enhances muscle tone, it is used to correct facial contours. The effect of mesotherapy procedures with this drug is the same as after a circular facelift. DMAE gives amazing results in the periorbital area: smoothes out crow's feet, lifts drooping eyelids. It is often used to easily increase lip volume by increasing tone and increasing blood circulation. After using dimethylaminoethanol, wrinkles on the lips and around the mouth disappear.

What problems does the drug solve?

Mesotherapy procedures with DMAE are indicated for:

• hyperpigmentation of the skin;
• deep wrinkles on the skin of the face and neck;
• sagging skin in the area of ​​the inner thighs, shoulders, abdomen;
• drooping oval face, presence of a double chin;
• puffiness under the eyes;
• decreased muscle tone of the face, neck, décolleté.

The drug is used after Botox injections to correct undesirable consequences.

The main advantage of DMAE mesotherapy is fast, noticeable and lasting results. The effect is visible after the second procedure, and another 2–4 sessions are required to consolidate it. Dimethylaminoethanol rarely causes allergic reactions. Cosmetic procedures with it are a relatively safe and gentle alternative to surgical intervention.

Methods and features of administration of DMAE

When administering the drug, you can use the nappage or papules technique, but it is more effective to inject directly into the muscles or muscle clusters. This is an unpleasant procedure, but the degree of its pain largely depends on the skill of the cosmetologist. An experienced master makes a small number of injections, but at certain points, thanks to which he covers all the necessary muscles. The procedure itself takes from 7 to 10 minutes. With proper manipulation, the swelling goes away within a couple of hours.

DMAE can be used both as a single drug and as an ingredient in cocktails. Dimethylaminoethanol combines well with silicon, coenzyme Q10, ferulic and hyaluronic acid, panthenol, and red grape extract. To avoid bruising after the injections, it is recommended to start drinking ascorutin two weeks before the expected session.

Contraindications to mesotherapy procedures are:

• pregnancy,
• breastfeeding period,
• hypertension,
• epilepsy,
• cholelithiasis,
• poor blood clotting,
• exacerbation of acne and herpes,
• individual intolerance.

You can get acquainted with the prices and choose a meso-cocktail in the section: “Meso-cocktails”

Dimethylaminoethanol (DMAE): at the pharmacy

Dimethylaminoethanol , unlike most dietary supplements, is not so easy to find in a pharmacy. As a rule, regular pharmacies boast a wide range of herbal nutritional supplements, such as St. John's wort or burdock root, and specialized drugs such as DMAE or Dehydroepiandrosterone (DHEA) or fat burners are much easier to purchase in specialized online stores. In addition to a large selection of natural dietary supplements, such stores have another advantage over regular pharmacies - more attractive prices. The pricing policy of reputable online stores is based on direct cooperation with global manufacturers of dietary supplements, which can significantly reduce their cost.

Dimethylaminoethanol (DMAE): instructions

Any food supplement, including DMAE , must be supplied with instructions that describe in detail the indications and rules for its use. And although dimethylaminoethanol is recognized as a relatively safe drug, this information should not be neglected.

Dimethylaminoethanol (DMAE): how to take

The effectiveness of DMAE largely depends on how you take it. Specific instructions on the amount and method of use of a particular product with dimethylaminoethanol are indicated in the annotation for the drug. Typically, the average dosage is 100 to 500 mg of DMAE per day, which can be taken in one or two doses.

As a rule, manufacturers recommend taking capsules or tablets in the first half of the day, with or separately from food, with the required amount of water. Sometimes, to clarify the dosage, it is necessary to consult a doctor, especially when it comes to treating children.

The results of the therapy become noticeable after 3 weeks of using DMAE , however, for the best effect, the course can last about 3 months. It is worth noting that in some cases DMAE can cause excessive stimulation of the nervous system, which can be expressed in muscle tension, headaches or insomnia, and although such side effects are quite rare, you should start taking the drug with small doses and gradually increase them to the required amount . As a rule, the body’s negative reaction to dimethylaminoethanol does not appear immediately, but during the first weeks of using the drug, so during this period you need to carefully monitor the condition of your body. If side effects occur, you should stop taking DMAE for 1-2 days and then resume it with a lower dose.

Dimethylaminoethanol (DMAE): reviews

Reviews of dimethylaminoethanol are very promising. People who have taken drugs with it to correct brain activity note their high effectiveness. According to them, already in the first week of use, coordination significantly improves, concentration increases, performance and clarity of thinking increase. Representatives of the fair sex pay tribute to the rejuvenating effect of DMAE . Women say that cosmetics with dimethylaminoethanol really noticeably transform aging facial skin, making it much more elastic and moisturized.

How DMAE works

During the digestion process, DMAE acts in two ways: A. In the liver, DMAE, under the influence of methionine, becomes choline, which already acts on acetylcholine. That is, an indirect action results.

B. In the intestines, this supplement is directly absorbed into the blood and enters the brain, also acting on acetylcholine. The second option suggests that DMAE increases the level of this neurotransmitter faster than when choline is absorbed from the liver. But this method is considered ineffective. So this supplement, when absorbed from the intestines, has a weak effect on acetylcholine. (www.ncbi.nlm.nihdotgov/pubmed/85012eight)

Once DMAE enters the bloodstream, the following occurs:

1. Passes the blood-brain barrier and enters the brain.
2. There is an increase in choline levels through inhibition of its transport from the blood. When there is a lot of choline in the blood, there is a lot of it in the central nervous system, and as a result, there is a lot of acetylcholine. If we “prevent the body from flushing choline out of the blood through the kidneys, liver, and intestines,” we increase its beneficial effect on the brain. But there is also evidence that excessive inhibition can harm the embryo, if there is one. (www.ncbi.nlmpointnih.gov/pubmed/1146026three)
3. DMAE, under the influence of the enzyme betaine homocysteine ​​methyltransferase (BHMT), partially becomes Dimethylglycine (DMG), which is used as a stimulant in sports, and Trimethylglycine (TMG) or Betaine, which acts mainly as a hepatoprotector.
4. DMAE inhibits/prohibits the transport and metabolism of choline into phosphocholine and phosphatidylcholine. Phosphatidylcholine is used to create membranes in the cells of the central nervous system. This is a very important process, inhibited for a long period of time can cause aging and death of nerve cells. This is like diluting cement with excess water or sand. A long period means a period of more than a year of regular use. However, with sufficient consumption of Phosphatidylcholine from a normal diet: eggs, nuts, fish, this negative effect of DMAE is reduced to zero.

   

To briefly summarize: DMAE enters the blood through the intestines and through the liver. Further, it partially produces choline and acetylcholine, partially Dimethylglycine and Trimethylglycine.