Consequences of Dysport: limitations and side effects

Youth injections have long been actively used by women in the USA and other countries; they began to be used in the CIS later. During this time, many who have tried anti-aging procedures undergo sessions again and again to look young and attractive. Now, without surgical intervention, it has become possible at any age, thanks to procedures with Botox or Dysport, to turn back the clock and maintain beauty.

In recent years, many new terms have appeared in the field of cosmetology and very often it is difficult to understand and figure out what the essence is, which procedures are better and more effective, safer for health? There is the opinion of experts, their reviews, which will help you find answers to your questions.

Contraindications

Hypersensitivity, myasthenia gravis, myasthenic and myasthenic-like syndromes (including Lambert-Eaton syndrome); soft tissue infections at the injection site, concomitant use of aminoglycosides or spectinomycin, pregnancy, lactation, children (up to 2 years), hypersensitivity to the components of the drug, generalized movement disorders, bleeding disorders, high myopia. It is not recommended to use the drug in patients over 60 years of age, in particular due to the higher risk of asymmetry[1].

How to treat

If the allergic reaction is expressed by local symptoms, it will be enough to take an antihistamine. However, before doing this, you must make sure that there are no more serious consequences.

If angioedema or anaphylactic shock develops, you must immediately call an ambulance. Despite the fact that such a symptom is rare, you need to know how to help the patient before specialists arrive.

First, the patient is given an antihistamine medication. Apply something cold to the area where the treatment took place; it is better to use ice. This will help narrow the blood vessels and relieve swelling.

It is necessary to open all windows in the room where the patient is located to ensure access to the required amount of fresh air.

Side effects

Local reactions: 2-5% - microhematomas (up to 7 days), pain at the injection site (up to 1 day). Systemic reactions when using the drug in a high dose (more than 250 units): general or local weakness (within 7 days), falls. In the treatment of blepharospasm, hemifacial spasm: ptosis (15-20%), lacrimation (0.5-1%), rarely - ectropion, keratitis, diplopia, entropion, ecchymosis in the soft tissues of the eyeball. When injected into both sternocleidomastoid muscles, dysphagia (2-5%) occurs. As a rule, these side effects do not require additional therapy and regress within 1 month after administration of the drug.

Overdose

Symptoms: General weakness, paresis of injected muscles. Specific botulinum antitoxin is effective within 30 minutes after injection; if necessary, resuscitation measures.

Features of drugs and causes of allergies

Botox and its analogues contain botulinum toxin type A. Statistics say that poor sensitivity to this substance occurs in a small number of people. In this case, the administration of even a small dose of the drug causes muscle paralysis. There is no evidence that injections of the drug can cause an allergic reaction. But similar problems may be associated with excipients contained in the drugs:

• original Botox, Relatox and Botulax contain a certain amount of human protein albumin;
• Dysport also consists of albumin and lactose.

Under the influence of these components, people with hypersensitivity develop a full-fledged allergic reaction. It has a mild course, but can affect the appearance and general condition of the body.

All modern Botox preparations must be diluted to a lower concentration by a specialist before administration. To do this, you should use only saline solution.

But inexperienced cosmetologists sometimes add lidocaine to the product. Such experiments sometimes lead to serious consequences, including anaphylactic shock.

There is also a lot of lidocaine contained in the cream, which is often applied before the injection to reduce discomfort. In this case, an allergy to Dysport and other Botox preparations may actually occur.

But botulinum toxin itself is not allergenic and is safe for health in small doses. Increased sensitivity is associated with auxiliary components, violations of the rules for preparing injections, and low qualifications of the cosmetologist.

special instructions

Injections of the drug must be carried out by a highly qualified doctor with special training and permission from the manufacturer. Injections can be performed on an outpatient basis in a treatment room.

Before prescribing the drug, anatomical features and any changes due to past surgical operations should be taken into account. Do not exceed recommended doses and frequency of administration.

Complications after injection are extremely rare and can occur when the needle injures vital structures (nerves, blood vessels, trachea) if the procedure is not performed properly.

Antibodies to the hemagglutinin complex of botulinum toxin are formed in 1-5% of patients after repeated injections. The formation of antibodies is facilitated by the administration of large doses of the drug (more than 250 units) at short intervals (less than 2 months), booster injections (small doses at short intervals). In case of formation of antibodies to botulinum toxin, other serological types are used.

Reduced blink rate due to injections of the drug into the orbicularis oculi muscle can lead to permanent epithelial damage and corneal ulceration, especially in patients with n.faciales disorders. The sensitivity of the cornea of ​​the eyes of previously operated patients should be carefully checked, injections into the lower eyelid area should be avoided to prevent its inversion and any epithelial defect should be actively treated. This may require protective drops, lubricants, soft contact lenses, an eye patch, or other measures.

Headache after Botox

After Botox injections, there are often complaints of a persistent, dull headache - cosmetologists consider this a normal phenomenon and explain it as follows:

• The body's reaction to injections. Damage to the skin with a high probability of being involved in injury to nerve endings and the walls of blood vessels is the reason for the occurrence of local and not too intense headaches. They go away on their own within 3 days maximum.
• Botox intolerance. This is recorded very rarely; more often, an inadequate reaction of the body occurs to the anesthetic cream that is used to treat the face before injections. In this case, the headache is accompanied by fluctuations in blood pressure (often it increases) and general weakness. A physician's assistance is required because prescriptions regarding antihistamines and duration of therapy will need to be obtained.
• Too much muscle tension. Occurs when a large dose of botulinum toxin is administered – the muscle fibers have to be strained more than usual. This leads to severe headaches that radiate to the eyes. The discomfort lasts for several days or weeks until the muscles get used to the new working conditions.

Mechanism of action of Botox
Headache after Botox may appear due to improper conduct of the rehabilitation period - for example, the patient drank alcohol immediately after injections, or there were other violations.

Use for cosmetic purposes

Wrinkles

The first study detailing the use of botulinum toxin in cosmetology was published in 1992.

Small muscles located under the skin, contracting, create wrinkles on the forehead, in the corners of the eyes, the bridge of the nose and the back of the nose, the upper lip, and cords on the neck.

As a result, botulinum toxin injections smooth out even stubborn and deep wrinkles by relaxing the overactive muscles involved in their formation by blocking the signals between these muscles and their motor nerves. Under the influence of botulinum neurotoxin, muscle motor activity weakens. Fine and deep wrinkles are smoothed out, and the surface of the skin becomes smooth.

To administer the drug, thin needles are used to inject the drug into the muscles. To numb the procedure, local anesthetics are used, which are first applied to the skin.

The drug begins to act on average after 7-14 days. The effect of the drug lasts from 2 to 8 months, after which the procedure must be repeated to restore the effect. With regular procedures, the muscles are kept relaxed, wrinkles of any depth are smoothed out and new ones do not form.

Despite its ability to reduce the signs of aging on the face, botulinum neurotoxin still has disadvantages. With this drug it is impossible to eliminate all wrinkles, but only facial (or dynamic) ones formed as a result of excessive muscle activity. For example, the area around the mouth, cheeks and chin are not the best places for botulinum toxin injections. To eliminate wrinkles in these areas, fillers or gels are used to fill the grooves of the wrinkles.

There is a technique called “mesobotox” - this is the subdermal administration of microdoses of the drug (micropapular). This technique allows you to smooth out fine purse-string wrinkles around the mouth.

Treatment of local hyperhidrosis

Hyperhidrosis of the palms, armpits, feet or face is often associated with endocrine disorders, neurological disorders, and hormonal changes in women. In some cases, excessive sweating can occur for no apparent reason, based on a genetic predisposition.

The most popular method of treating excessive sweating with injections is based on the use of botulinum toxin. Injected into the problem area, the drug blocks the transmission of nerve impulses and blocks the work of the sweat glands. In conditions of lack of response to external stimuli, the amount of sweat produced is significantly reduced.

Therapy is local in nature. It does not disrupt the sweating process of the entire body, but acts in specific problem areas. Typically, the injection method is used to treat sweating of the armpits, hands, face and feet. The procedure, performed with thin needles, is relatively painless, does not cause complications and has a narrow range of contraindications. The effect of the procedure becomes available within 2-4 days and lasts stably from six months to one and a half years.

Complications of cosmetic use of botulinum neurotoxin

Fatalities associated with botulinum neurotoxin injections were described in a February 2008 FDA report. The American Academy of Dermatology also noted that by 2003, there were 28 deaths reported related to the medical use of botulinum neurotoxin injections.

Complications of botulinum neurotoxin administration are few and extremely rare. If the drug is administered in excess, the corner of the mouth or eyelid may droop. However, given the reversibility of the action of the neurotoxin, if these side effects occur, restoration of appearance occurs after 1-2 months.

How is the introduction procedure carried out?

For cosmetic use, Dysport® is available in the form of a lyophilisate, consisting of:

• The main component is botulinum toxin A (there is also a “wild” type B, used in the production of Myobloc injections).
• Excipients: albumin with lactose.

After diluting the powder, the solution cannot be stored, since it does not contain preservatives, and cannot be frozen, since side effects from using such a drug are possible. Therefore, if a cosmetologist in a salon offers to carry out aesthetic correction at any time convenient for you, this is a reason to be wary. Typically, to use a bottle of the drug, several clients make an appointment on a specific day.

Dysport® is administered on an outpatient basis. But despite the relative ease of use, you should definitely choose a specialist carefully. Men and athletes need more botulinum toxin. This is due to the speed of muscle recovery and the speed of metabolism in the body.

An experienced doctor will calculate the required number of units of the drug and the location of the injection points individually for a particular person in such a way that there will be no “mask effect”. The facial expressions will remain, but the wrinkles will be smoothed out. A natural facial expression is a sign of competent use of botulinum therapy.

On this topic

• Dysport

Is it possible to inject Dysport during pregnancy?

• Inna Viktorovna Zhikhoreva
• August 2, 2020

Botulinum toxin protein is a neurotoxic poison that affects the central nervous system in large doses. Therefore, the muscle relaxant must be administered by a qualified esthetician with a training certificate from the manufacturer Dysport®.

Moreover, botulinum therapy refers to aesthetic medicine procedures, which only specialists with higher medical education (as opposed to cosmetology) have the right to perform. In addition to the certificate, you can ask the doctor for a case study of his work, in which examples of “before and after” will be clearly visible.

The procedure is as follows:

1. Examination , determination of contraindications, dosages. This is the longest part.
2. Filling out questionnaires and signing informed consent for the session, which indicates the injection sites and the number of units of the corrective agent.
3. Applying injection points and, if desired by the client, a local anesthetic - anesthetic cream. 1-4 areas of the face can be treated in one session. For each - a maximum of 20 units.
4. Injection of the solution into the desired places with a special thin needle.
5. Apply ice for 5-10 minutes to avoid bruising and swelling.

Then the cosmetologist will give instructions on how to behave after Dysport® injections.

Thus, the procedure itself takes little time. But the effect will last from 2-3 months or even longer, depending on the amount of medicine administered and the individual properties of the body.

On the day of administration, the following rules should be observed:

1. Do not take a horizontal position for 4-5 o'clock.
2. Do not touch injection sites. In general, postpone all salon procedures for several weeks.
3. Skip going to the sauna or bathhouse.
4. Do not sunbathe, neither in the sun nor in a solarium.
5. Refrain from smoking, spicy foods, alcohol, strong coffee and tea.
6. Exercise circulation , which should be avoided.

The results of the injections will be noticeable on the second day. After 2 weeks the effect will be pronounced. During this period, you should be observed by a cosmetologist.